PT (INR) Test
Coagulation management
About the parameter
PT (INR) test kit is used for the determination of prothrombin complex-activity in whole blood according to Owren. It is ideal for monitoring of oral anticoagulation with vitamin-K inhibitors like Warfarin or Marcumar.
PT, according to Owren, measures the combined activity of the vitamin-K dependent coagulation factors II, VII and X. In analysis, the sample is mixed with thromboplastin, CaCl, fibrinogen and coagulation factor V.
The clotting time is prolonged on the therapeutical level (<0.4 IU/mL) of factor II, V and X in the sample, but the assay is insensitive to heparin in therapeutical levels up to 1.0 IE/mL.
Overview
Method
Photometrical clot detection.
Measurement range
1 – 8 INR
ISI: ~1.00 (lot dependent)
Test duration
Test duration takes approx. 1:45 minutes at INR = 1.
Package insert
More details can be found in the package insert.
Please note: All package inserts provided on this website are intended for information purposes only! Always process all tests, controls and calibrators strictly according to the package insert provided with the kit.
Appropriate instruments
 CUBE |
 CUBE-S |
 smart 700/340 |
 smart 700/546 |
Evaluation
Assay evaluation
Find the evaluation study for the Eurolyser PT (INR) assay here: Evaluation Eurolyser PT (INR)
Please note: depending on the time of the market launch of an assay, the respective assay evaluation was carried out using either a Eurolyser smart instrument or a Eurolyser CUBE instrument.
Since the measurement method is the same in both instruments (their photometric units are identical in construction), as was proved in this comparison study, all testkit evaluations provided on this website are valid for either instrument!
Additional information
Article Numbers
ST 0180 PT (INR) test kit (containing 32 tests)
ST 1800 PT (INR) test kit (low/high)